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KMID : 1040620200260040670
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Clinical and Molecular Hepatology
2020 Volume.26 No. 4 p.670 ~ p.676
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Liver-lung axes in alcohol-related liver disease
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Arteel Gavin E.
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Abstract
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Alcohol-related liver disease (ALD) and alcohol-related susceptibility to acute lung injury are the leading causes of morbidity and mortality due to chronic alcohol abuse. Most commonly, alcohol-induced injury to both organs are evaluated independently, although they share many parallel mechanisms of injury. Moreover, recent studies indicate that there is a potential liver lung axis that may contribute to organ pathology. This mini-review explores established and potential mechanisms of organ-organ crosstalk in ALD and alcohol-related lung injury.
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KEYWORD
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Liver diseases, Alcoholic Liver disease, Acute lung injury, Respiratory distress syndrome, Adult
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